Stress‐induced increase of monoclonal antibody production in CHO cells

Abstract Monoclonal antibodies (mAbs) are of great interest to the biopharmaceutical industry due to their widely used application as human therapeutic and diagnostic agents. As such, mAb require to exhibit human‐like glycolization patterns. Therefore, recombinant Chinese hamster ovary (CHO) cells a...

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Bibliografiset tiedot
Päätekijät: Jana Schellenberg, Tamanna Nagraik, Ole Jacob Wohlenberg, Sebastian Ruhl, Janina Bahnemann, Thomas Scheper, Dörte Solle
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Wiley-VCH 2022-05-01
Sarja:Engineering in Life Sciences
Aiheet:
cell size
cell‐specific productivity
CHO
mAb
stress
Linkit:https://doi.org/10.1002/elsc.202100062
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