Stress‐induced increase of monoclonal antibody production in CHO cells

Abstract Monoclonal antibodies (mAbs) are of great interest to the biopharmaceutical industry due to their widely used application as human therapeutic and diagnostic agents. As such, mAb require to exhibit human‐like glycolization patterns. Therefore, recombinant Chinese hamster ovary (CHO) cells a...

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Detalhes bibliográficos
Main Authors: Jana Schellenberg, Tamanna Nagraik, Ole Jacob Wohlenberg, Sebastian Ruhl, Janina Bahnemann, Thomas Scheper, Dörte Solle
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley-VCH 2022-05-01
Colecção:Engineering in Life Sciences
Assuntos:
cell size
cell‐specific productivity
CHO
mAb
stress
Acesso em linha:https://doi.org/10.1002/elsc.202100062
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