Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK.

As a major diarrheagenic human pathogen, enterohemorrhagic Escherichia coli (EHEC) produce attaching and effacing (A/E) lesions, characterized by the formation of actin pedestals, on mammalian cells. A bacterial T3SS effector NleL from EHEC O157:H7 was recently shown to be a HECT-like E3 ligase in v...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Xiangpeng Sheng, Qing You, Hongnian Zhu, ZeNan Chang, Qingrun Li, Haifeng Wang, Chen Wang, Hongyan Wang, Lijian Hui, Chongtao Du, Xiaoduo Xie, Rong Zeng, Anning Lin, Dongfang Shi, Kangcheng Ruan, Jinghua Yan, George Fu Gao, Feng Shao, Ronggui Hu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2017-07-01
Colecção:PLoS Pathogens
Acesso em linha:http://europepmc.org/articles/PMC5549993?pdf=render
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados