Chronic Activation of LXRα Sensitizes Mice to Hepatocellular Carcinoma

The oxysterol receptor liver X receptor (LXR) is a nuclear receptor best known for its function in the regulation of lipid and cholesterol metabolism. LXRs, both the α and β isoforms, have been suggested as potential therapeutic targets for several cancer types. However, there was a lack of report o...

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Main Authors: Yang Xie, Runzi Sun, Li Gao, Jibin Guan, Jingyuan Wang, Aaron Bell, Junjie Zhu, Min Zhang, Meishu Xu, Peipei Lu, Xinran Cai, Songrong Ren, Pengfei Xu, Satdarshan P. Monga, Xiaochao Ma, Da Yang, Yulan Liu, Binfeng Lu, Wen Xie
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2022-05-01
Colecção:Hepatology Communications
Acesso em linha:https://doi.org/10.1002/hep4.1880
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