Bioactive Dietary VDR Ligands Regulate Genes Encoding Biomarkers of Skin Repair That Are Associated with Risk for Psoriasis

Treatment with 1,25-dihydroxyvitamin D3 (1,25D) improves psoriasis symptoms, possibly by inducing the expression of late cornified envelope (LCE)3 genes involved in skin repair. In psoriasis patients, the majority of whom harbor genomic deletion of LCE3B and LCE3C (LCE3C_LCE3B-del), we propose that...

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主要な著者: Amitis Karrys, Islam Rady, Roxane-Cherille N. Chamcheu, Marya S. Sabir, Sanchita Mallick, Jean Christopher Chamcheu, Peter W. Jurutka, Mark R. Haussler, G. Kerr Whitfield
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2018-02-01
シリーズ:Nutrients
主題:
vitamin D receptor
late cornified envelope genes
docosahexaenoic acid
curcumin
epidermis
keratinocytes
psoriasis treatment
nutraceuticals
differentiation
activator protein-1
オンライン･アクセス:http://www.mdpi.com/2072-6643/10/2/174
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