Bioactive Dietary VDR Ligands Regulate Genes Encoding Biomarkers of Skin Repair That Are Associated with Risk for Psoriasis

Treatment with 1,25-dihydroxyvitamin D3 (1,25D) improves psoriasis symptoms, possibly by inducing the expression of late cornified envelope (LCE)3 genes involved in skin repair. In psoriasis patients, the majority of whom harbor genomic deletion of LCE3B and LCE3C (LCE3C_LCE3B-del), we propose that...

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Main Authors: Amitis Karrys, Islam Rady, Roxane-Cherille N. Chamcheu, Marya S. Sabir, Sanchita Mallick, Jean Christopher Chamcheu, Peter W. Jurutka, Mark R. Haussler, G. Kerr Whitfield
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI AG 2018-02-01
Sraith:Nutrients
Ábhair:
vitamin D receptor
late cornified envelope genes
docosahexaenoic acid
curcumin
epidermis
keratinocytes
psoriasis treatment
nutraceuticals
differentiation
activator protein-1
Rochtain Ar Líne:http://www.mdpi.com/2072-6643/10/2/174
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