The Intrinsically Disordered W Protein Is Multifunctional during Henipavirus Infection, Disrupting Host Signalling Pathways and Nuclear Import

Nipah and Hendra viruses are highly pathogenic, zoonotic henipaviruses that encode proteins that inhibit the host’s innate immune response. The W protein is one of four products encoded from the P gene and binds a number of host proteins to regulate signalling pathways. The W protein is intrinsicall...

Full description

Saved in:
Bibliographic Details
Main Authors: Sofiya Tsimbalyuk, Emily M. Cross, Mikayla Hoad, Camilla M. Donnelly, Justin A. Roby, Jade K. Forwood
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
intrinsically disordered
W protein
henipaviruses
STAT
IRF-3
Online Access:https://www.mdpi.com/2073-4409/9/8/1913
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items