The Relationship between the PI3K/Akt/mTOR Signal Transduction Pathway and Non-small Cell Lung Cancer

Background and objective It has been known that abnormality of PI3K/Akt/mTOR signal pathway plaied an important role in the oncogenesis of lung cancer. In this study, we tried to detect the mRNA expression levels of VEGF, PI3K, Akt, mTOR gene, the key genes of PI3K/Akt/mTOR signal pathway, in human...

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Detalhes bibliográficos
Main Authors: Wentao YUE, Xiaomin WANG, Yue WANG
Formato: Artigo
Idioma:Chinês
Publicado em: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2009-04-01
Colecção:Chinese Journal of Lung Cancer
Assuntos:
Lung neoplasms
Vascular endothelial growth factor A
Human 1-phosphatidylinositol 3-kinase p110 subunit
Oncogene protein v-akt
Mammalian target of rapamycin (mTOR)
Acesso em linha:http://www.lungca.org/index.php?journal=01&page=article&op=view&path%5B%5D=10.3779%2Fj.issn.1009-3419.2009.04.10&path%5B%5D=269
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