Sex Differences of Oxidative Stress to Cholestatic Liver and Kidney Injury in Young Rats

Sexual dimorphism plays a role in the liver and in renal injuries. However, whether sex is a risk factor in bile duct ligation (BDL) in young rats has never been examined. Methods: Six male and six female rats treated with BDL were sacrificed 2 weeks after surgery and were designated as BDL-M and BD...

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Main Authors: Kow-Aung Chang, I-Chun Lin, Jiunn-Ming Sheen, Yu-Chieh Chen, Chih-Cheng Chen, You-Lin Tain, Chih-Sung Hsieh, Li-Tung Huang
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2013-04-01
Serija:Pediatrics and Neonatology
Teme:
asymmetric dimethylarginine
bile duct ligation
cationic amino acid transporter
nitric oxide
sexual dimorphism
Online dostop:http://www.sciencedirect.com/science/article/pii/S1875957212001830
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