A new system for parallel drug screening against multiple-resistant HIV mutants based on lentiviral self-inactivating (SIN) vectors and multi-colour analyses

<p>Abstract</p> <p>Background</p> <p>Despite progress in the development of combined antiretroviral therapies (cART), HIV infection remains a significant challenge for human health. Current problems of cART include multi-drug-resistant virus variants, long-term toxicity...

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Autori principali: Prokofjeva Maria M, Riecken Kristoffer, Spirin Pavel V, Yanvarév Dimitriy V, Düsedau Arne, Ellinger Bernhard, Fehse Boris, Stocking Carol, Prassolov Vladimir S
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2013-01-01
Serie:AIDS Research and Therapy
Soggetti:
HIV
Drug resistance
Drug screening
Lentiviral vectors
Accesso online:http://www.aidsrestherapy.com/content/10/1/1
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