HLA alleles modulate EBV viral load in multiple sclerosis

Abstract Background The etiopathology of multiple sclerosis (MS) is believed to include genetic and environmental factors. Human leukocyte antigen (HLA) alleles, in particular,  are associated with disease susceptibility, whereas Epstein Barr Virus (EBV) infection has long been suspected to play a r...

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Autores principales: Simone Agostini, Roberta Mancuso, Franca R. Guerini, Sandra D’Alfonso, Cristina Agliardi, Ambra Hernis, Milena Zanzottera, Nadia Barizzone, Maurizio A. Leone, Domenico Caputo, Marco Rovaris, Mario Clerici
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2018-03-01
Colección:Journal of Translational Medicine
Materias:
Epstein-Barr virus
HLA-class I alleles
HLA-A*02
HLA-B*07
Multiple sclerosis
Immunogenetics
Acceso en línea:http://link.springer.com/article/10.1186/s12967-018-1450-6
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