HLA alleles modulate EBV viral load in multiple sclerosis

Abstract Background The etiopathology of multiple sclerosis (MS) is believed to include genetic and environmental factors. Human leukocyte antigen (HLA) alleles, in particular,  are associated with disease susceptibility, whereas Epstein Barr Virus (EBV) infection has long been suspected to play a r...

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Hlavní autoři: Simone Agostini, Roberta Mancuso, Franca R. Guerini, Sandra D’Alfonso, Cristina Agliardi, Ambra Hernis, Milena Zanzottera, Nadia Barizzone, Maurizio A. Leone, Domenico Caputo, Marco Rovaris, Mario Clerici
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2018-03-01
Edice:Journal of Translational Medicine
Témata:
Epstein-Barr virus
HLA-class I alleles
HLA-A*02
HLA-B*07
Multiple sclerosis
Immunogenetics
On-line přístup:http://link.springer.com/article/10.1186/s12967-018-1450-6
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