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Unc45b forms a cytosolic complex with Hsp90 and targets the unfolded myosin motor domain.

Myosin folding and assembly in striated muscle is mediated by the general chaperones Hsc70 and Hsp90 and a myosin specific co-chaperone, UNC45. Two UNC45 genes are found in vertebrates, including a striated muscle specific form, Unc45b. We have investigated the role of Unc45b in myosin folding. Epit...

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Hlavní autoři: Rajani Srikakulam, Li Liu, Donald A Winkelmann
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2008-05-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC2377097?pdf=render
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