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Unc45b forms a cytosolic complex with Hsp90 and targets the unfolded myosin motor domain.
Myosin folding and assembly in striated muscle is mediated by the general chaperones Hsc70 and Hsp90 and a myosin specific co-chaperone, UNC45. Two UNC45 genes are found in vertebrates, including a striated muscle specific form, Unc45b. We have investigated the role of Unc45b in myosin folding. Epit...
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Hlavní autoři: | , , |
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Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Public Library of Science (PLoS)
2008-05-01
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Edice: | PLoS ONE |
On-line přístup: | http://europepmc.org/articles/PMC2377097?pdf=render |
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