A randomised, double-blind, parallel-group trial to assess mercaptopurine versus placebo to prevent or delay recurrence of Crohn’s disease following surgical resection (TOPPIC)

Background: Crohn’s disease (CD) is a chronic, relapsing, inflammatory bowel disease. Up to 65% of patients with CD require an operation to control the disease within 10 years. Both endoscopic and clinical recurrence is common within 2 years of operation, with re-operation rates cumulating at 5% of...

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Bibliografische gegevens
Hoofdauteurs: Jack Satsangi, Nicholas A Kennedy, Craig Mowat, Ian Arnott, Catriona Keerie, Steff Lewis, Holly Ennis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: NIHR Journals Library 2017-09-01
Reeks:Efficacy and Mechanism Evaluation
Onderwerpen:
crohn’s disease
mercaptopurine
postoperative recurrence
Online toegang:https://doi.org/10.3310/eme04040
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