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3 β-hydroxysteroid-Δ 24 reductase (DHCR24) protects neuronal cells from apoptotic cell death induced by endoplasmic reticulum (ER) stress.

3β-Hydroxysteroid-Δ24 reductase (DHCR24) is an endoplasmic reticulum (ER)-localized multifunctional enzyme that possesses anti-apoptotic and cholesterol-synthesizing activities. Accumulating evidence suggests that ER stress is involved in the pathogenesis of neurodegenerative disease. In this study,...

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Main Authors: Xiuli Lu, Yang Li, Weiqi Wang, Shuchao Chen, Ting Liu, Dan Jia, Xiaoping Quan, Deliang Sun, Alan K Chang, Bing Gao
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2014-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC3906068?pdf=render
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