Two distinct cellular pathways leading to endothelial cell cytotoxicity by silica nanoparticle size

Abstract Background Silica nanoparticles (SiNPs) are widely used for biosensing and diagnostics, and for the targeted delivery of therapeutic agents. Safety concerns about the biomedical and clinical applications of SiNPs have been raised, necessitating analysis of the effects of their intrinsic pro...

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Hlavní autoři: Kyungmin Lee, Jangwook Lee, Minjeong Kwak, Young-Lai Cho, Byungtae Hwang, Min Ji Cho, Na Geum Lee, Jongjin Park, Sang-Hyun Lee, Jong-Gil Park, Yeon-Gu Kim, Jang-Seong Kim, Tae-Su Han, Hyun-Soo Cho, Young-Jun Park, Seon-Jin Lee, Hee Gu Lee, Won Kon Kim, In Cheul Jeung, Nam Woong Song, Kwang-Hee Bae, Jeong-Ki Min
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2019-02-01
Edice:Journal of Nanobiotechnology
Témata:
Silica nanoparticles
Apoptosis
Necroptosis
ROS
Autophagy
On-line přístup:http://link.springer.com/article/10.1186/s12951-019-0456-4
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