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Stochastic model of integrin-mediated signaling and adhesion dynamics at the leading edges of migrating cells.
Productive cell migration requires the spatiotemporal coordination of cell adhesion, membrane protrusion, and actomyosin-mediated contraction. Integrins, engaged by the extracellular matrix (ECM), nucleate the formation of adhesive contacts at the cell's leading edge(s), and maturation of nasce...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science (PLoS)
2010-02-01
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| Seria: | PLoS Computational Biology |
| Dostęp online: | http://europepmc.org/articles/PMC2829041?pdf=render |
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