Irisin protects cardiomyocytes against hypoxia/reoxygenation injury via attenuating AMPK mediated endoplasmic reticulum stress

Abstract Endoplasmic reticulum (ER) stress plays a central role in myocardial ischemia/reperfusion (I/R) injury. Irisin has been reported to have protective properties in ischemia disease. In this study, we aimed at investigating whether irisin could alleviate myocardial I/R injury by ER stress atte...

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Main Authors: Rongchuan Yue, Mingming Lv, Meide Lan, Zaiyong Zheng, Xin Tan, Xuemei Zhao, Yulong Zhang, Jun Pu, Lei Xu, Houxiang Hu
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2022-05-01
Serija:Scientific Reports
Online dostop:https://doi.org/10.1038/s41598-022-11343-0
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