Downregulation of TLR4 by miR-181a Provides Negative Feedback Regulation to Lipopolysaccharide-Induced Inflammation

Acute lung injury (ALI) is a progressive clinical disease with a high mortality rate, and characterized by an excessive uncontrolled inflammatory response. MicroRNAs (miRNAs) play a critical role in various human inflammatory diseases, and have been recognized as important regulators of inflammation...

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Detalhes bibliográficos
Main Authors: Kangfeng Jiang, Shuai Guo, Tao Zhang, Yaping Yang, Gan Zhao, Aftab Shaukat, Haichong Wu, Ganzhen Deng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-02-01
Colecção:Frontiers in Pharmacology
Assuntos:
acute lung injury
miR-181a
LPS
NF-κB
ROS
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fphar.2018.00142/full
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