Magnoflorine Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via Suppressing NF-κB and MAPK Activation

Acute lung injury (ALI) which is featured by a strong pulmonary inflammation, is a major cause of morbidity and mortality in critically ill patients. Magnoflorine, a quaternary alkaloid isolated from Chinese herb Magnolia or Aristolochia, has been reported to have potent anti-inflammatory properties...

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Detalhes bibliográficos
Main Authors: Shuai Guo, Kangfeng Jiang, Haichong Wu, Chao Yang, Yaping Yang, Jing Yang, Gan Zhao, Ganzhen Deng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-08-01
Colecção:Frontiers in Pharmacology
Assuntos:
magnoflorine
anti-inflammation
ALI
LPS
NF-κB
MAPK
Acesso em linha:https://www.frontiersin.org/article/10.3389/fphar.2018.00982/full
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