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Endothelial edema precedes blood-brain barrier breakdown in early time points after experimental focal cerebral ischemia
Abstract In the setting of stroke, ischemia-related blood-brain barrier (BBB) dysfunction aggravates the cerebral edema, which critically impacts on the clinical outcome. Further, an impaired vascular integrity is associated with the risk of intracranial bleeding, especially after therapeutic recana...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
BMC
2019-02-01
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Series: | Acta Neuropathologica Communications |
Assuntos: | |
Acceso en liña: | http://link.springer.com/article/10.1186/s40478-019-0671-0 |
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