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Endothelial edema precedes blood-brain barrier breakdown in early time points after experimental focal cerebral ischemia

In the setting of stroke, ischemia-related blood-brain barrier (BBB) dysfunction aggravates the cerebral edema, which critically impacts on the clinical outcome. Further, an impaired vascular integrity is associated with the risk of intracranial bleeding, especially after therapeutic recanalization....

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Détails bibliographiques
Publié dans:Acta Neuropathol Commun
Auteurs principaux: Krueger, Martin, Mages, Bianca, Hobusch, Constance, Michalski, Dominik
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369548/
https://ncbi.nlm.nih.gov/pubmed/30744693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0671-0
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