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Endothelial edema precedes blood-brain barrier breakdown in early time points after experimental focal cerebral ischemia

In the setting of stroke, ischemia-related blood-brain barrier (BBB) dysfunction aggravates the cerebral edema, which critically impacts on the clinical outcome. Further, an impaired vascular integrity is associated with the risk of intracranial bleeding, especially after therapeutic recanalization....

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Krueger, Martin, Mages, Bianca, Hobusch, Constance, Michalski, Dominik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369548/
https://ncbi.nlm.nih.gov/pubmed/30744693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0671-0
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