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Myelin-related gene silencing mediated by LPA1 – Rho/ROCK signaling is correlated to acetylation of NFκB in S16 Schwann cells
Lysophosphatidic acid (LPA) initiates demyelination following peripheral nerve injury, which causes neuropathic pain. Our previous in vivo and ex vivo studies using mice have demonstrated that LPA-induced demyelination of spinal dorsal roots is attributed by the LPA1-type receptor-mediated down-regu...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016-10-01
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| Colecção: | Journal of Pharmacological Sciences |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S1347861316301189 |
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