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Hormesis in Cholestatic Liver Disease; Preconditioning with Low Bile Acid Concentrations Protects against Bile Acid-Induced Toxicity.

INTRODUCTION:Cholestasis is characterized by accumulation of bile acids and inflammation, causing hepatocellular damage. Still, liver damage markers are highest in acute cholestasis and drop when this condition becomes chronic, indicating that hepatocytes adapt towards the hostile environment. This...

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Main Authors: Esther M Verhaag, Manon Buist-Homan, Martijn Koehorst, Albert K Groen, Han Moshage, Klaas Nico Faber
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2016-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC4780766?pdf=render
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