Epidemiologic, Phenotypic, and Structural Characterization of Aminoglycoside-Resistance Gene <i>aac(3)-IV</i>

Aminoglycoside antibiotics are powerful bactericidal therapeutics that are often used in the treatment of critical Gram-negative systemic infections. The emergence and global spread of antibiotic resistance, however, has compromised the clinical utility of aminoglycosides to an extent similar to tha...

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Main Authors: Michel Plattner, Marina Gysin, Klara Haldimann, Katja Becker, Sven N. Hobbie
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Assuntos:
antimicrobial resistance
aminoglycosides
apramycin
acetyltransferase
<i>aac(3)-IV</i>
Acceso en liña:https://www.mdpi.com/1422-0067/21/17/6133
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