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The Kinetic Mechanism of AAC(3)-IV Aminoglycoside Acetyltransferase from Escherichia coli

The aminoglycoside 3-N-acetyltransferase AAC(3)-IV from Escherichia coli exhibits a very broad aminoglycoside specificity, causing resistance to a large number of aminoglycosides, including the atypical veterinary antibiotic, apramycin. We report here on the characterization of the substrate specifi...

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Détails bibliographiques
Auteurs principaux: Magalhaes, Maria L. B., Blanchard, John S.
Format: Artigo
Langue:Inglês
Publié: 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593831/
https://ncbi.nlm.nih.gov/pubmed/16331988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi051777d
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