A human beta cell line with drug inducible excision of immortalizing transgenes

Objectives: Access to immortalized human pancreatic beta cell lines that are phenotypically close to genuine adult beta cells, represent a major tool to better understand human beta cell physiology and develop new therapeutics for Diabetes. Here we derived a new conditionally immortalized human beta...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Marion Benazra, Marie-José Lecomte, Claire Colace, Andreas Müller, Cécile Machado, Severine Pechberty, Emilie Bricout-Neveu, Maud Grenier-Godard, Michele Solimena, Raphaël Scharfmann, Paul Czernichow, Philippe Ravassard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2015-12-01
Reeks:Molecular Metabolism
Onderwerpen:
Cell engineering
Human pancreatic beta cell line
Conditional immortalization
Tamoxifen inducible CRE
Human beta cell function
Online toegang:http://www.sciencedirect.com/science/article/pii/S2212877815001787
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items