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XPO1 expression worsens the prognosis of unfavorable DLBCL that can be effectively targeted by selinexor in the absence of mutant p53
Abstract The XPO1 inhibitor selinexor was recently approved in relapsed/refractory DLBCL patients but only demonstrated modest anti-DLBCL efficacy, prompting us to investigate the prognostic effect of XPO1 in DLBCL patients and the rational combination therapies in high-risk DLBCL. High XPO1 express...
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| 主要な著者: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BMC
2020-11-01
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| シリーズ: | Journal of Hematology & Oncology |
| 主題: | |
| オンライン・アクセス: | http://link.springer.com/article/10.1186/s13045-020-00982-3 |
| タグ: |
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