The degree of segmental aneuploidy measured by total copy number abnormalities predicts survival and recurrence in superficial gastroesophageal adenocarcinoma.

Prognostic biomarkers are needed for superficial gastroesophageal adenocarcinoma (EAC) to predict clinical outcomes and select therapy. Although recurrent mutations have been characterized in EAC, little is known about their clinical and prognostic significance. Aneuploidy is predictive of clinical...

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Main Authors: Jon M Davison, Melissa Yee, J Michael Krill-Burger, Maureen A Lyons-Weiler, Lori A Kelly, Christin M Sciulli, Katie S Nason, James D Luketich, George K Michalopoulos, William A LaFramboise
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3894223?pdf=render
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