Protective Effects of 2-Dodecyl-6-Methoxycyclohexa-2,5 -Diene-1,4-Dione Isolated from Averrhoa Carambola L. (Oxalidaceae) Roots on High-Fat Diet-Induced Obesity and Insulin Resistance in Mice

Background/Aims: The roots of Averrhoa carambola L. (Oxalidaceae) have long been used as a traditional Chinese medicine for the treatment of diabetes and diabetes-related diseases. 2-dodecyl-6-methoxycycyclohexa-2,5-1,4-dione (DMDD) has been isolated from A. carambola L. roots, and this study was ca...

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Main Authors: Juman Li, Xiaojie Wei, Qiuqiao Xie, Thi Thai Hoa Pham, Jinbin Wei, Ping He, Yang Jiao, Xiaohui Xu, Thi Huong Giang Nguyen, Qingwei Wen, Renbin Huang
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Physiol Biochem Press GmbH & Co KG 2016-12-01
Colecção:Cellular Physiology and Biochemistry
Assuntos:
2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione
Obesity
Insulin resistance
TLR4
Inflammatory cytokines
Acesso em linha:http://www.karger.com/Article/FullText/453156
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