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Glycolipid binding preferences of Shiga toxin variants.

The major virulence factor of Shiga toxin producing E. coli, is Shiga toxin (Stx), an AB5 toxin that consists of a ribosomal RNA-cleaving A-subunit surrounded by a pentamer of receptor-binding B subunits. The two major isoforms, Stx1 and Stx2, and Stx2 variants (Stx2a-h) significantly differ in toxi...

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Main Authors: Sayali S Karve, Alison A Weiss
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science (PLoS) 2014-01-01
Sraith:PLoS ONE
Rochtain Ar Líne:http://europepmc.org/articles/PMC4077739?pdf=render
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