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CovS inactivation reduces CovR promoter binding at diverse virulence factor encoding genes in group A Streptococcus.
The control of virulence gene regulator (CovR), also called caspsule synthesis regulator (CsrR), is critical to how the major human pathogen group A Streptococcus fine-tunes virulence factor production. CovR phosphorylation (CovR~P) levels are determined by its cognate sensor kinase CovS, and functi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2022-02-01
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| Colecção: | PLoS Pathogens |
| Acesso em linha: | https://doi.org/10.1371/journal.ppat.1010341 |
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