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Use of a Phosphorylation Site Mutant To Identify Distinct Modes of Gene Repression by the Control of Virulence Regulator (CovR) in Streptococcus pyogenes

Control of the virulence regulator/sensor kinase (CovRS) two-component system (TCS) serves as a model for investigating the impact of signaling pathways on the pathogenesis of Gram-positive bacteria. However, the molecular mechanisms by which CovR, an OmpR/PhoB family response regulator, controls vi...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Horstmann, Nicola, Sahasrabhojane, Pranoti, Yao, Hui, Su, Xiaoping, Shelburne, Samuel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573087/
https://ncbi.nlm.nih.gov/pubmed/28289082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00835-16
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