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Functional network analysis of p85 and PI3K as potential gene targets and mechanism of oleanolic acid in overcoming breast cancer resistance to tamoxifen

Abstract Background Tamoxifen resistance in estrogen receptor positive (ER+) breast cancer therapy increases, which is the leading cause of cancer treatment failure, as it can impair patients’ prognoses, cause cancer recurrence, metastasis, and death. Combination therapy with compounds is needed to...

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Detalhes bibliográficos
Main Authors: Wilfan Ibadurrahman, Naufa Hanif, Adam Hermawan
Formato: Artigo
Idioma:Inglês
Publicado em: SpringerOpen 2022-04-01
Colecção:Journal of Genetic Engineering and Biotechnology
Assuntos:
Acesso em linha:https://doi.org/10.1186/s43141-022-00341-4
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