Relation of EGFR/PI3K/AKT signaling components with tamoxifen efficacy in patients with estrogen-dependent breast cancer

Background. It is generally accepted that crosstalk between the growth factor receptor and ER pathways implicated in tamoxifen resistance. The aim of the study was to examine the relationship between mRNA level, protein expression and gene polymorphism of the EGFR/PI3K/AKT signaling components with...

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Main Authors: T. A. Dronova, N. N. Babyshkina, M. V. Zavyalova, S. V. Patalyak, E. M. Slonimskaya, N. V. Cherdyntseva, J. G. Kzhyshkowska
Formato: Artigo
Idioma:Russo
Publicado em: ABV-press 2018-11-01
Colecção:Uspehi Molekulârnoj Onkologii
Assuntos:
estrogen-dependent breast cancer
tamoxifen
egfr/pi3k/akt signaling
gene polymorphism
Acesso em linha:https://umo.abvpress.ru/jour/article/view/164
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