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The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil

<p>Abstract</p> <p>Background</p> <p>Metabolic reprogramming resulting in enhanced glycolysis is a phenotypic trait of cancer cells, which is imposed by the tumor microenvironment and is linked to the down-regulation of the catalytic subunit of the mitochondrial H<su...

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Bibliografiske detaljer
Main Authors: Cuezva José M, Sánchez-Aragó María
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2011-02-01
Serier:Journal of Translational Medicine
Online adgang:http://www.translational-medicine.com/content/9/1/19
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