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Long-term stability of clopidogrel solid dispersions-Importance of in vitro dissolution test.
Formulation of solid dispersions (SDs), in which the drug substance is dissolved or dispersed inside a polymer matrix, is one of the modern approaches to increase the solubility and dissolution rate of poorly soluble active pharmaceutical ingredients (APIs), such as clopidogrel. In the form of a fre...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science (PLoS)
2022-01-01
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Colecção: | PLoS ONE |
Acesso em linha: | https://doi.org/10.1371/journal.pone.0266237 |
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