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Long-term stability of clopidogrel solid dispersions-Importance of in vitro dissolution test.

Formulation of solid dispersions (SDs), in which the drug substance is dissolved or dispersed inside a polymer matrix, is one of the modern approaches to increase the solubility and dissolution rate of poorly soluble active pharmaceutical ingredients (APIs), such as clopidogrel. In the form of a fre...

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Detalhes bibliográficos
Main Authors: Ehlimana Osmanović Omerdić, Larisa Alagić-Džambić, Marko Krstić, Maja Pašić-Kulenović, Đorđe Medarević, Branka Ivković, Dragana Vasiljević
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2022-01-01
Colecção:PLoS ONE
Acesso em linha:https://doi.org/10.1371/journal.pone.0266237
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