ACSL4 deficiency confers protection against ferroptosis-mediated acute kidney injury

The term ferroptosis coined in 2012 causes acute kidney injury (AKI). However, its pathway mechanism in AKI is poorly understood. In this study, we conducted an RNA-sequence analysis of kidneys in AKI and normal mice to explore the pathway mechanism of ferroptosis. Consequently, differentially expre...

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Autors principals: Yue Wang, Menghan Zhang, Ran Bi, Yali Su, Fei Quan, Yanting Lin, Chongxiu Yue, Xinmeng Cui, Qixiang Zhao, Siliang Liu, Yong Yang, Dayong Zhang, Qiuhua Cao, Xinghua Gao
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2022-05-01
Col·lecció:Redox Biology
Matèries:
ACSL4
Acute kidney injury
Ferroptosis
Macrophages
HIF-1α
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2213231722000349
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