ACSL4 deficiency confers protection against ferroptosis-mediated acute kidney injury

The term ferroptosis coined in 2012 causes acute kidney injury (AKI). However, its pathway mechanism in AKI is poorly understood. In this study, we conducted an RNA-sequence analysis of kidneys in AKI and normal mice to explore the pathway mechanism of ferroptosis. Consequently, differentially expre...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yue Wang, Menghan Zhang, Ran Bi, Yali Su, Fei Quan, Yanting Lin, Chongxiu Yue, Xinmeng Cui, Qixiang Zhao, Siliang Liu, Yong Yang, Dayong Zhang, Qiuhua Cao, Xinghua Gao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2022-05-01
Cyfres:Redox Biology
Pynciau:
ACSL4
Acute kidney injury
Ferroptosis
Macrophages
HIF-1α
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2213231722000349
Tagiau: Ychwanegu Tag
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