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Pharmacokinetic interactions of esaxerenone with amlodipine and digoxin in healthy Japanese subjects
Abstract Background To investigate the effects of coadministration of esaxerenone with amlodipine on the pharmacokinetics (PK) of each drug, and of esaxerenone on the PK of digoxin. Methods In three open-label, single-sequence, crossover studies, healthy Japanese males received single oral doses of...
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Главные авторы: | , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
BMC
2020-07-01
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Серии: | BMC Pharmacology and Toxicology |
Предметы: | |
Online-ссылка: | http://link.springer.com/article/10.1186/s40360-020-00423-4 |
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