Pharmacokinetic interactions of esaxerenone with amlodipine and digoxin in healthy Japanese subjects

Abstract Background To investigate the effects of coadministration of esaxerenone with amlodipine on the pharmacokinetics (PK) of each drug, and of esaxerenone on the PK of digoxin. Methods In three open-label, single-sequence, crossover studies, healthy Japanese males received single oral doses of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yoshiaki Kirigaya, Masanari Shiramoto, Tomoko Ishizuka, Hinako Uchimaru, Shin Irie, Manabu Kato, Takako Shimizu, Takafumi Nakatsu, Yasuhiro Nishikawa, Hitoshi Ishizuka
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2020-07-01
Saila:BMC Pharmacology and Toxicology
Gaiak:
Esaxerenone
Drug interactions
Pharmacokinetics
Digoxin
Amlodipine
Sarrera elektronikoa:http://link.springer.com/article/10.1186/s40360-020-00423-4
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak