Abcc6 deficiency in mice leads to altered ABC transporter gene expression in metabolic active tissues

Abstract Background ATP-binding cassette (ABC) transporters are involved in a huge range of physiological processes. Mutations in the ABCC6 gene cause pseudoxanthoma elasticum, a metabolic disease with progressive soft tissue calcification. Methods The aim of the present study was to analyze gene ex...

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Main Authors: Bettina Ibold, Isabel Faust, Janina Tiemann, Theo G. M. F. Gorgels, Arthur A. B. Bergen, Cornelius Knabbe, Doris Hendig
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-01-01
Colecção:Lipids in Health and Disease
Assuntos:
Abcc6
Pseudoxanthoma elasticum
Gene expression
ATP-binding cassette transporters
Mice
Acesso em linha:http://link.springer.com/article/10.1186/s12944-018-0943-x
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http://link.springer.com/article/10.1186/s12944-018-0943-x

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