The release of cardioprotective humoral factors after remote ischemic preconditioning in humans is age- and sex-dependent

Abstract Background Preclinical and proof-of-concept studies suggest a cardioprotective effect of remote ischemic preconditioning (RIPC). However, two major clinical trials (ERICCA and RIPHeart) failed to show cardioprotection by RIPC. Aging and gender might be confounding factors of RIPC affecting...

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Main Authors: André Heinen, Friederike Behmenburg, Aykut Aytulun, Maximilian Dierkes, Lea Zerbin, Wolfgang Kaisers, Maximilian Schaefer, Tanja Meyer-Treschan, Susanne Feit, Inge Bauer, Markus W. Hollmann, Ragnar Huhn
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2018-04-01
Series:Journal of Translational Medicine
Assuntos:
Cardioprotection
Remote ischemic preconditioning
Age
Sex
Reperfusion injury
Acceso en liña:http://link.springer.com/article/10.1186/s12967-018-1480-0
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