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Atorvastatin promotes bone formation in aged apoE–/– mice through the Sirt1–Runx2 axis
Abstract Background Statins are the most widely used drugs in elderly patients; the most common clinical application of statins is in aged hyperlipemia patients. There are few studies on the effects and mechanisms of statins on bone in elderly mice with hyperlipemia. The study is to examine the effe...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BMC
2020-08-01
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| Серии: | Journal of Orthopaedic Surgery and Research |
| Предметы: | |
| Online-ссылка: | http://link.springer.com/article/10.1186/s13018-020-01841-0 |
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