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Kynurenine Promotes RANKL–Induced Osteoclastogenesis In Vitro by Activating the Aryl Hydrocarbon Receptor Pathway

There is increasing evidence of the involvement of the tryptophan metabolite kynurenine (KYN) in disrupting osteogenesis and contributing to aging-related bone loss. Here, we show that KYN has an effect on bone resorption by increasing osteoclastogenesis. We have previously reported that in vivo tre...

詳細記述

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書誌詳細
主要な著者: Nada H. Eisa, Sakamuri V. Reddy, Ahmed M. Elmansi, Galina Kondrikova, Dmitry Kondrikov, Xing-Ming Shi, Chad M. Novince, Mark W. Hamrick, Meghan E. McGee-Lawrence, Carlos M. Isales, Sadanand Fulzele, William D. Hill
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2020-10-01
シリーズ:International Journal of Molecular Sciences
主題:
AhR
オンライン・アクセス:https://www.mdpi.com/1422-0067/21/21/7931
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