Kynurenine Promotes RANKL–Induced Osteoclastogenesis In Vitro by Activating the Aryl Hydrocarbon Receptor Pathway

There is increasing evidence of the involvement of the tryptophan metabolite kynurenine (KYN) in disrupting osteogenesis and contributing to aging-related bone loss. Here, we show that KYN has an effect on bone resorption by increasing osteoclastogenesis. We have previously reported that in vivo tre...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Nada H. Eisa, Sakamuri V. Reddy, Ahmed M. Elmansi, Galina Kondrikova, Dmitry Kondrikov, Xing-Ming Shi, Chad M. Novince, Mark W. Hamrick, Meghan E. McGee-Lawrence, Carlos M. Isales, Sadanand Fulzele, William D. Hill
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2020-10-01
Seri Bilgileri:International Journal of Molecular Sciences
Konular:
Kynurenine
AhR
osteoclast
NFATc1
c-fos
Online Erişim:https://www.mdpi.com/1422-0067/21/21/7931
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller