The Molecular and Neuropathological Consequences of Genetic Risk for Alzheimer's Dementia

Alzheimer's dementia commonly impacts the health of older adults and lacks any preventative therapy. While Alzheimer's dementia risk has a substantial genetic component, the specific molecular mechanisms and neuropathologies triggered by most of the known genetic variants are unclear. Resu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Shinya Tasaki, Chris Gaiteri, Sara Mostafavi, Philip L. De Jager, David A. Bennett
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2018-10-01
Sarja:Frontiers in Neuroscience
Aiheet:
Alzheimer's disease
polygenic risk score
PheWAS
brain pathology
multi omics
epigenome
Linkit:https://www.frontiersin.org/article/10.3389/fnins.2018.00699/full
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia