Загрузка...
HES1 is a novel downstream modifier of the SHH-GLI3 Axis in the development of preaxial polydactyly.
Sonic Hedgehog/GLI3 signaling is critical in regulating digit number, such that Gli3-deficiency results in polydactyly and Shh-deficiency leads to digit number reductions. SHH/GLI3 signaling regulates cell cycle factors controlling mesenchymal cell proliferation, while simultaneously regulating Grem...
Сохранить в:
| Главные авторы: | , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science (PLoS)
2021-12-01
|
| Серии: | PLoS Genetics |
| Online-ссылка: | https://doi.org/10.1371/journal.pgen.1009982 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|