Immunoprofiling in Neuroendocrine Neoplasms Unveil Immunosuppressive Microenvironment

Checkpoint inhibitors have shown promising results in a variety of tumors; however, in neuroendocrine tumors (NET) and neuroendocrine carcinomas (NEC), low response rates were reported. We aimed herein to investigate the tumor immune microenvironment in NET/NEC to determine whether checkpoint pathwa...

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Detalhes bibliográficos
Main Authors: Antonia Busse, Liliana H. Mochmann, Christiane Spenke, Ruza Arsenic, Franziska Briest, Korinna Jöhrens, Hedwig Lammert, Bence Sipos, Anja A. Kühl, Ralph Wirtz, Marianne Pavel, Michael Hummel, Daniel Kaemmerer, Richard P. Baum, Patricia Grabowski
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-11-01
Colecção:Cancers
Assuntos:
ileal neuroendocrine tumors
neuroendocrine carcinoma
immunoprofiling
tumor infiltrating lymphocytes
programmed cell death protein 1
programmed death-ligand 1
Acesso em linha:https://www.mdpi.com/2072-6694/12/11/3448
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