The Enhanced Cytotoxic and Pro-Apoptotic Effects of Optimized Simvastatin-Loaded Emulsomes on MCF-7 Breast Cancer Cells

Statins, including simvastatin (SMV), are commonly used for the control of hyperlipidaemia and have also proven therapeutic and preventative effects in cardiovascular diseases. Besides that, there is an emerging interest in their use as antineoplastic drugs as demonstrated by different studies showi...

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Main Authors: Zuhier A. Awan, Usama A. Fahmy, Shaimaa M. Badr-Eldin, Tarek S. Ibrahim, Hani Z. Asfour, Mohammed W. Al-Rabia, Anas Alfarsi, Nabil A. Alhakamy, Wesam H. Abdulaal, Hadeel Al Sadoun, Nawal Helmi, Ahmad O. Noor, Filippo Caraci, Diena M. Almasri, Giuseppe Caruso
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-06-01
Colecção:Pharmaceutics
Assuntos:
simvastatin
cell cycle
apoptosis
emulsomes
cytotoxicity
breast cancer
Acesso em linha:https://www.mdpi.com/1999-4923/12/7/597
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